Physical modelling to assess the effect of micropulse modes of laser radiation at the chorioretinal complex of the human eye based on the theory of activated complex

Purpose: to construct a physical model based on the theory of activated complex (TAC) with indicators ΔH and ΔS mentioned in works G.I. Zheltov his colleagues so as assess impact laser radiation micropulse modes at chorioretinal (CRC), well compare it models Arrhenius integral results mode testing using autofluorescence method.Material methods. Modeling degree damage CRC adjacent structures was carried out Eyring equation. Values = 360 000 J/mol 890 J/mol·deg for proteins other RPE organic were determined by co-authors vivo series experiments primates. For modeling, absorption coefficient 460 cm–1 used, wavelength 577 nm – 10-micron-thick layer transmission 37 %. Micropulse (50 μs, 2.4 %, 10 ms, 100 mkm, 0.4–1.9 W) performed Navilas 577s navigation patients aged 35–46 appearance types 2–3 Fitzpatrick scale; this assessed short-wave (488 nm) method.Results. A TAC constructed. Results modeling injury depending power coincide according method. The average equal 440 years type scale clarified. Conclusion. computer equation structures, which are described co-authors, has shown high compliance micro-pulse real patients. does not require adjustment any free parameters unlike approaches equation; also allows find coefficients small sample level structures.